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The method of isolating the active ingredient, cocaine hydrochloride, was principal accomplished in the mid-19th century. Chemists like Albert Niemann in Germany and Paolo Mantegazza in Italy played vital roles in pioneer investigation and discovery. At near the lately 1800s, cocaine was being against in medical treatments, manifestly as a shire anesthetic, and was uniform promoted about eminent figures like Sigmund Freud, who believed it had therapeutic potential. Degree, as its addictive properties became evident, governments began to direct and eventually criminalize its advantage by the untimely 20th century.
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